Hepatic clearance measured with ( 99 m ) Tc - GSA single - photon emission computed tomography
نویسندگان
چکیده
AIM: To evaluate the clinical utility of hepatic clearance (HC) measured with technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl human serum albumin (Tc-GSA) single-photon emission computed tomography (SPECT) to estimate the degree of liver
منابع مشابه
99mTc-GSA liver dynamic SPECT for the preoperative assessment of hepatectomy.
OBJECTIVE The purpose of the present study was to devise a predictive index to predict residual liver function before hepatic resection, using technetium-99m diethylenetriamine-penta-acetic acid-galactosyl human serum albumin (99mTc-GSA) liver dynamic single photon emission computed tomography (SPECT). METHODS Fifty-seven patients with liver disease underwent liver dynamic SPECT with 99mTc-GS...
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The objective of this study was to investigate clinical utility of a graphical method for estimating liver uptake and blood retention of 99mTc-DTPA-galactosyl human serum albumin (99mTc-GSA; DTPA is diethylenetriaminepentaacetic acid) using dynamic single photon emission computed tomography (SPECT) data. When considering the kinetics of 99mTc-GSA, if it is assumed that (1) 99mTc-GSA distributes...
متن کاملQuantitative assessment of hepatic function during liver regeneration in a standardized rat model.
UNLABELLED Reliable assessment of hepatic function during liver regeneration is crucial after liver surgery or liver transplantation. (99m)Tc-galactosyl human serum albumin ((99m)Tc-GSA) scintigraphy, (99m)Tc-mebrofenin hepatobiliary scintigraphy (HBS), the indocyanine green (ICG) clearance test, and the galactose elimination capacity (GEC) are common quantitative liver function tests. However,...
متن کاملBinding rate constant of Tc-99m DTPA galactosyl human serum albumin measured by quantitative dynamic SPECT--clinical evaluation as a total and regional liver function test.
To evaluate the clinical utility of a new method with dynamic single photon emission computed tomography (SPECT) and scatter and attenuation compensation to estimate both total and regional liver function quantitatively. Five controls, 20 patients with chronic liver disease, and 2 patients with Budd-Chiari syndrome were studied. Dynamic liver SPECT data were acquired during 20 minutes after inj...
متن کاملReliability and advantages of using non-uniform Chang’s attenuation correction method using a CT-based attenuation coefficient map in 99mTc-GSA SPECT/CT hepatic imaging
BACKGROUND Generally, attenuation correction is made by incorporating a linear attenuation coefficient, which is based on the attenuation coefficient map (mu-map) created from a computed tomography scan, into the ordered subsets-expectation maximization reconstruction method in non-uniform domains. A non-uniform Chang's attenuation correction method that uses the mu-map created from a computed ...
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